Lung Cancer Symptoms, Types, Causes, Treatment & Diagnosis
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- Ceritinib or alectinib is typically given if the cancer becomes resistant to crizotinib or if the patient is unable to tolerate crizotinib.
- The bronchi branch into progressively smaller airways called bronchioles that end in tiny sacs known as alveoli where gas exchange occurs.
- occurred and over 142,000 deaths were due to the disease.
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Ceritinib or alectinib istypically given if the cancer becomes resistant to crizotinib or if the patientis unable to tolerate crizotinib. What is Lung cancer? Cancer of the Lung, like all cancers, results from an abnormality in the body's basic unit of life, the cell. Normally, the body maintains a system of checks and balances on cell growth so that cells divide to produce new cells only when new cells are needed. Disruption of this system of checks and balances on cell growth results in an uncontrolled division and proliferation of cells that eventually forms a mass known as a tumor. Tumors can be benign or malignant; when we speak of "cancer," we are referring to malignant tumors. Medical professionals can usually remove benign tumors, and these tumors do not spread to other parts of the body. Malignant tumors, on the other hand, often grow aggressively locally where they start, but tumor cells also can enter into the bloodstream or lymphatic system and then spread to other sites in the body. This process of spread is termed metastasis; the areas of tumor growth at these distant sites are called metastases. Since Lung cancer tends to spread or metastasize very early after it forms, it is a very life-threatening cancer and one of the most difficult cancers to treat. While Lung cancer can spread to any organ in the body, certain locations -- particularly the adrenal glands, liver, brain, and bones -- are the most common sites for Lung cancer metastasis. The Lung also is a very common site for metastasis from malignant tumors in other parts of the body. The same types of cells as the original (primary) tumor make up tumor metastases. For example, if prostate cancer spreads via the bloodstream to the Lungs, it is metastatic prostate cancer in the Lung and is not Lung cancer. The principal function of the Lungs is to exchange gases between the air we breathe and the blood. Through the Lung, carbon dioxide is removed from the bloodstream and oxygen enters the bloodstream. The right Lung has three lobes, while the left Lung has two lobes and a small structure called the lingula that is the equivalent of the middle lobe on the right. The major airways entering the Lungs are the bronchi, which arise from the trachea, which is outside the Lungs. The bronchi branch into progressively smaller airways called bronchioles that end in tiny sacs known as alveoli where gas exchange occurs. A thin layer of tissue called the pleura covers the Lungs and chest wall. Lung cancers can arise in any part of the Lung, but 90%-95% of cancers of the Lung arise from the epithelial cells, the cells lining the larger and smaller airways (bronchi and bronchioles); for this reason, Lung cancers are sometimes called bronchogenic cancers or bronchogenic carcinomas. (Carcinoma is another term for cancer.) Cancers also can arise from the pleura (called mesotheliomas) or rarely from supporting tissues within the Lungs, for example, the blood vessels. Source: iStock/ MedicineNet / American Cancer Society How common is Lung cancer? Lung cancer is the most common cause of death due to cancer in both men and women throughout the world. Statistics from the American Cancer Society estimated that in zweitausendneunzehn there will be about 228,000 new cases of Lung cancer in the U.S. occurred and over 142,000 deaths were due to the disease.
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