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Headline:    

The placebo effect: is there something in it after all?

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3 Minutes, 27 Seconds

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Your article has been created in English language

Main Topic keyword:    

Placebo effect inert cause and effect

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Placebo effect inert cause and effect

Topics of your individual article:    

effect ✓ found ✓ basis ✓ real ✓ brain ✓ responders ✓ involved ✓ study ✓ placebo ✓ region ✓ people ✓ patients ✓ Baliki ✓ taking ✓ pain

Summary:    

The idea that a useless sugar pill or harmless saline injection could result in a measurable improvement in a patients symptoms, sometimes as good as taking an active drug, has been so hard to explain that some have even doubted whether it can be real. Several studies are pointing to a biological basis for the placebo effect, with the latest research focused on a region of the brain known as the mid-frontal gyrus, which runs along the frontal lobes just above the eyes. But if this is difficult to explain, then what about the noncebo, the evil twin of the placebo, where a sugar pill actually makes people feel worse because they expect to suffer the side effects they have heard about?

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Researchers at Northwestern University in Chicago have found that a region of the brain known as the mid-frontal gyrus which runs along the frontal lobes just above the eyes is involved in the placebo effect. Source: https://www.artikelschreiber.com/en/.", "mainEntityOfPage": { "@type": "WebPage", "@id": "https://www.artikelschreiber.com/en/#webpage" }, "publisher": { "@type": "Organization", "@id": "https://www.artikelschreiber.com/en/#organization", "url": "https://www.artikelschreiber.com/en/", "name": "ArtikelSchreiber.com", "description": "Your free SEO text generator | ArtikelSchreiber.com", "logo": { "@type": "ImageObject", "@id": "https://www.artikelschreiber.com/en/#logo", "url": "https://www.artikelschreiber.com/images/logo.png", "width": 531, "height": 628 }, "image": { "@type": "ImageObject", "@id": "https://www.artikelschreiber.com/en/#logo", "url": "https://www.artikelschreiber.com/images/logo.png", "width": 531, "height": 628 }, "sameAs": [ "https://www.unaique.net/" ] }, "keywords": "effect, found, basis, real, brain, responders, involved, study, placebo, region, people, patients, Baliki, taking, pain", "author": { "@type": "Person", "name": "ArtikelSchreiber.com", "url": "https://www.artikelschreiber.com/en/", "sameAs": [ "https://www.unaique.net/" ] }, "@id": "https://www.artikelschreiber.com/en/#links", "commentCount": "0", "sameAs": [ "https://www.artikelschreiber.com/", "https://www.artikelschreiber.com/en/", "https://www.artikelschreiber.com/es/", "https://www.artikelschreiber.com/fr", "https://www.artikelschreiber.com/it", "https://www.artikelschreiber.com/ru/", "https://www.artikelschreiber.com/zh", "https://www.artikelschreiber.com/jp/", "https://www.artikelschreiber.com/ar", "https://www.artikelschreiber.com/hi/", "https://www.artikelschreiber.com/pt/", "https://www.artikelschreiber.com/tr/" ], "speakable": { "@type": "SpeakableSpecification", "xpath": [ "/html/head/title", "/html/head/meta[@name='description']/@content" ] } } </script> </p><br /><br /> The placebo effect remains one of the most baffling mysteries in medicine. The idea that a useless sugar pill or harmless saline injection could result in measurable improvement in a patient's symptoms, sometimes as good as taking an active drug, has been so hard to explain that some have even doubted whether it can be real. Researchers at Northwestern University in Chicago have found that a region of the brain known as the mid-frontal gyrus, which runs along the frontal lobes just above the eyes, is involved in the placebo effect. The study, carried out by Marwan Baliki and Vania Apkarian, involved a small number of chronic-pain patients with osteoarthritis of knee. Researchers have identified a brain region that can predict the propensity of a patient's response to a placebo within the wider patient population suffering from chronic pain. They found that an area within mid-frontal gyrus lit up or, in their words, "showed a higher functional connectivity" in patients who responded to the placebo, compared with non-responders. Researchers have found that a brain region called the 'hotspot' can predict pain analgesia to an active drug. "We also examined the specificity of our results by testing whether this hotspot. . . can predict. . . pain. . . to. . . active drug," they said. The findings suggest a biological basis for the placebo effect and raise the prospect of tests to see if individuals are going to be good placebo responders. Scientists have identified a brain region involved in the placebo effect, which could lead to identifying placebo responders so that they don't get included in clinical trials. It's based on the idea that certain signalling pathways in brain, especially those involved with the "reward" network, help to mediate the 'placebo effect'. A new study has found that taking a placebo for chronic lower back pain can work effectively for some people even when they are told that the treatment is just a "powerful placebo". The study, conducted by researchers at the University of California, San Diego, found the placebo reduced initial pain and disability by about 30%. A study in 2011 found that placebo inhalers had no effect on increasing lung function. However, asthma patients nevertheless reported that they felt significantly better after using a "useless" inhaler. The study was conducted on over 1,000 patients with asthma. It was followed by a follow-up study on the same number of patients. If that is found to be the case, things could get really interesting.
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https://www.theguardian.com/science/2016/nov/06/placebo-effect-is-there-something-in-it

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